Viruses are responsible for many common and serious human diseases. Bioinformatics approaches are necessary to support collection of large amounts of data from diverse sources, management of such data through storage in databases using data-warehousing principles, and to provide a means for systematic study of the data, which can support experimental validation.

Viral Variome Analyzer (ViVA) is a systematic bioinformatics approach as an ecosystem to understand viral diversity and map targets that can facilitate diagnostic, surveillance, drug and vaccine design by processing the large amounts of viral sequence data and metadata produced by genomics, proteomics, and host-pathogen interaction studies, available in public databases, which are continuing to grow rapidly.

The portal is intended to be a major resource for local and global efforts towards monitoring and control of viruses.